Sven Hennig and colleagues published on covalent bicyclization of quaternary protein complexes

Congratulations to our member Sven Hennig and his colleagues Tom Grossmann (Biomimetic Chemistry) from the Vrije Universiteit Amsterdam and Saskia Neubacher (incircular) for the publications on the covalent bicyclization of quaternary protein complexes in Chem. Great work in which they show not only the successful crosslinking and stabilization of the Pseudomonas fluorescens esterase (Pfe) trimer via the INCYPRO technology, but also solved its crystal structure (PDB ID 8pi1).

Posted in From the lab, NVK.